Chamberbitter Supplement

Scientific Name: Phyllanthus urinaria

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Order: Malpighiales

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Family: Phyllanthaceae

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A species of Phyllanthus that is native to South and Southeast Asia. Chamberbitter is also known as gripeweed. The "urinaria" in its botanical name comes from its historical (and current) use to treat kidney and urinary stones. Similar to Phyllanthus amarus and Phyllanthus niruri, this plant is also being used to treat hepatitis B and other liver problems. However, do not confuse this plant with Phyllanthus amarus and Phyllanthus niruri.

Strong:

insufficient information

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Good:

insufficient information

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Promising:

insufficient information

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Conflicting (Unclear):

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Limited Evidence:

• Diabetes [1]
• Hepatitis B [2-3]
• Nonalcoholic Fatty Liver Disease [4]
• Stomach Problems [5]

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No Evidence:

insufficient information

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No Clinical Research:

All other conditions.

Side effects may include:

• Side effects have not been studied.

Precautions and Adverse Events:

• Use caution or contact a licensed healthcare practitioner, since there is not enough research on the use of supplements containing chamberbitter.

There is not enough research on the use of supplements containing chamberbitter during pregnancy and breast-feeding, so consult a licensed healthcare practitioner before use or avoid use.

Major:

insufficient information

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Moderate:

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Potential:

insufficient information

Chamberbitter is not a "drug", the best doses have not been thoroughly established. Make sure to follow the specific product instructions and take as directed on the label, or consult a licensed healthcare practitioner before use.

[Afendi et al. 2012]

1. Lans CA. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus. J Ethnobiol Ethnomed. 2006 Oct 13;2:45. 2. Chan HL, Sung JJ, Fong WF, Chim AM, Yung PP, et al. Double-blinded placebo-controlled study of Phyllanthus urinaris for the treatment of chronic hepatitis B. Aliment Pharmacol Ther. 2003 Aug 1;18(3):339-45. 3. Wang M, Cheng H, Li Y, Meng L, Zhao G, et al. Herbs of the genus Phyllanthus in the treatment of chronic hepatitis B: observations with three preparations from different geographic sites. J Lab Clin Med. 1995 Oct;126(4):350-2. 4. Wong VW, Wong GL, Chan AW, Chu WC, Choi PC, et al. Treatment of non-alcoholic steatohepatitis with Phyllanthus urinaria: a randomized trial. J Gastroenterol Hepatol. 2013 Jan;28(1):57-62. 5. Lans C. Comparison of plants used for skin and stomach problems in Trinidad and Tobago with Asian ethnomedicine. J Ethnobiol Ethnomed. 2007 Jan 5;3:3. 6. Afendi FM, Okada T, Yamazaki M, Hirai-Morita A, Nakamura Y, Nakamura K, Ikeda S, Takahashi H, Altaf-Ul-Amin M, Darusman LK, Saito K, Kanaya S. KNApSAcK family databases: integrated metabolite-plant species databases for multifaceted plant research. Plant Cell Physiol. 2012 Feb;53(2):e1.