Overview of Reishi Mushroom
Botanical Name: Ganoderma lucidum
Reishi or lingzhi is a mushroom found on dead or dying trees. It is valued in Asia for its medicinal properties. Ganoderic acid may be the active compound.
- Immune Stimulant [1-8]
- Immune Stimulant in Cancer Patients, reishi with citronellol / dang shen (Codonopsis pilosula) / Angelica sinensis, and another species, Ganoderma tsugae, with Angelica sinensis / rose geranium
- Reishi in combination with cordyceps / cat’s claw water extract / Grifola blazei / Grifola frondosa / Trametes versicolor / nicotinamide / zinc also had immune enhancing properties
Conflicting (Unclear):insufficient information
- Alters Pulse 
- Anti-Diabetic 
- Asthma, with reishi / Sophora flavescens / Glycyrrhiza uralensis 
- Arthritis 
- Cold Sores, reishi combined with Wisteria floribunda / Trapa natans / Terminalia chebulae / Coicis lachryma-jobi / Elfuinga applanata [13-14]
- Colorectal Cancer [15-16]
- Coronary Heart Disease [17-18]
- Focal Segmental Glomerulosclerosis (leading cause of kidney failure in adults) 
- Genital Herpes, reishi combined with Wisteria floribunda / Trapa natans / Terminalia chebulae / Coicis lachryma-jobi / Elfuinga applanata [20-21]
- Lower Urinary Tract Symptoms (LUTS), reishi at 6mg doses seemed to be effective [22-23]
- Neurasthenia 
- Prostate Cancer, reishi with chrysanthemum / isatis / licorice /Panax pseudoginseng / Rabdosia rubescens / saw palmetto / scutellaria 
- Shingles, reishi alone and reishi with Wisteria floribunda / Trapa natans / Miristica agrans / Coicis lachryma-jobi / Elfuinga applanata / Panax ginseng / Punica granatum [26-27]
No Evidence:insufficient information
No Clinical Research:All other conditions.
- Allergic Reactions
- Avoid or contact a licensed healthcare practitioner, if you are allergic to mold and/or mushrooms.
- There were several cases of abnormal elevation of serum CA72-4 (which is associated with the presence of cancerous cells) of cancer patients who had been within the normal range before taking reishi. After discontinuation of reishi, the patients were again within the normal range. The long-term effect of reishi on these patients is unknown.
- Reishi appears to not be harmful; including not being harmful to the liver and kidneys; however, there have been a few cases of liver failure.
- A related species Ganoderma neo-japonicum caused pancytopenia, which was reversible.
- There was a case of severe diarrhea in a patient with non-Hodgkin’s lymphoma.
- Several cases of allergic reactions have been caused by reishi.
- Reishi appears to NOT increase the risk of bleeding.
There is not enough research on the use of supplements containing reishi during pregnancy and breast-feeding, so consult a licensed healthcare practitioner before use or avoid use.
Reishi is not a "drug", the best doses have not been thoroughly established. Make sure to follow the specific product instructions and take as directed on the label, or consult a licensed healthcare practitioner before use.
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